IL-3 human
SIGMA/SRP4134 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Synonym: HCGF; IL-3; Interleukin-3; MCGF (Mast cell growth factor); MGC79398; Multi-CSF; P-cell stimulation factor
MDL Number: MFCD00147276
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| ≥98% (SDS-PAGE) | |
| biological source | human |
| form | lyophilized |
| impurities | endotoxin, tested |
| mol wt | ~15.0 kDa |
| NCBI accession no. | P08700   |
| packaging | pkg of 10 μg |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Interleukin-3 (IL-3) is a hematopoietic growth factor. The gene encoding it is localized on human chromosome 5. It has a role in cell proliferation and activates different signaling cascades. It is crucial for the differentiation of hematopoietic-derived endothelial progenitor cells (EPCs). The differentiation of erythroid cells, mast cells and granulocytes is stimulated by IL-3. The protein has been linked to schizophrenia. |
| General description: | IL-3 is a species-specific colony-stimulating factor that stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. Recombinant human IL-3 is a 15.0 kDa protein containing 133 amino acid residues. |
| Physical form: | Lyophilized without additives. |
| Preparation Note: | Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
| Preparation Note: | Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC); ≥98% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |