VEGF165 from rat
SIGMA/SRP4365 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
Synonym: MGC70609; VEGF; VEGF-A; VPF; Vascular endothelial growth factor A; Vascular permeability factor
Product Type: Chemical
VEGF Pathway Research areas: Angiogenesis, Metastasis, Hypoxia, Osteogenesis, Developmental biology Disease areas: Cancer, Osteoporosis, Ischemic stroke, Inflammation, Rheumatoid Arthritis, Diabetes See also: SRP3182; SRP4363; V5765; SRP4634; SRP4364; SRP4365, SRP3184
| assay | ≥98% (SDS-PAGE) |
| biological source | rat |
| form | lyophilized |
| impurities | endotoxin, tested |
| mol wt | ~38.4 kDa |
| NCBI accession no. | P16612   |
| packaging | pkg of 10 μg |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| Application: | VEGF165 (vascular endothelial growth factor 165) has been used to study the effects of VEGF on the morphology and survival of neurons and glial cells. |
| Biochem/physiol Actions: | VEGF165 (vascular endothelial growth factor 165) has been shown to have pro-angiogenic properties. It has a role in the proliferation of endothelial cells and neuroprotection. |
| General description: | VEGF165 (vascular endothelial growth factor 165), also known as VEGF-A, is a homodimeric glycoprotein and is expressed as multiple splice variants. Recombinant rat VEGF is a double, non-glycosylated, polypeptide containing 164 amino acids and having a molecular mass of 38.4kDa. |
| Physical form: | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5 |
| Preparation Note: | Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
| Preparation Note: | Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |