SDF-1alpha (CXCL12) from mouse
SIGMA/SRP4388 - recombinant, expressed in E. coli, ≥99% (SDS-PAGE), ≥99% (HPLC)
Synonym: CXCL12; PBSF; Pre-B cell growth-stimulating factor; SDF-1; chemokine (C-X-C motif) ligand 12; hIRH
MDL Number: MFCD01867605
Product Type: Chemical
assay | ≥99% (HPLC) |
≥99% (SDS-PAGE) | |
biological source | mouse |
form | lyophilized |
impurities | endotoxin, tested |
mol wt | ~7.9 kDa |
NCBI accession no. | P40224 ![]() ![]() |
packaging | pkg of 10 μg |
potency | 50-100 ng/mL |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage condition | avoid repeated freeze/thaw cycles |
storage temp. | −20°C |
Biochem/physiol Actions: | Stromal Cell-Derived Factor-1α (SDF-1α) is a pleiotropic chemokine. It works as a chemoattractant for T- and B-lymphocytes and inflammatory monocytes. In neural stem cells, SDF-1α is needed for proliferation, survival, migration, intercellular interaction and guidance to neuronal axon. It is responsible for pathogenic inflammation in the central nervous system (CNS). It also controls BMP (bone morphogenic protein)-associated osteogenic differentiation. |
General description: | Stromal Cell-Derived Factor-1α (SDF-1α) is a recently discovered protein belonging to the α-chemokine (C-X-C) family of cytokines. Recombinant mouse SDF-1α is a 7.9kDa protein containing 68 amino acids residues. |
Physical form: | Lyophilized from 10 mM acetic acid. The protein may appear as a haze or film, which is difficult to see at the bottom of the vial. |
Reconstitution: | Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
Reconstitution: | Reconstitution in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99% (HPLC); ≥99% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |