gAcrp30/Adiponectin human
SIGMA/SRP4591 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
Synonym: Acrp30; Adipocyte-specific protein AdipoQ; Adipolean; Apm-1; adipoQ; adiponectin
Product Type: Chemical
assay | ≥98% (SDS-PAGE) |
biological source | human |
form | lyophilized |
impurities | endotoxin, tested |
mol wt | ~16.6 kDa |
NCBI accession no. | NM_004797 ![]() ![]() |
packaging | pkg of 25 μg |
potency | <1-3 μg/mL |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage condition | avoid repeated freeze/thaw cycles |
storage temp. | −20°C |
UniProt accession no. | Q15848 ![]() ![]() |
Biochem/physiol Actions: | In obese mice and humans, adiponectin mRNA expression is reduced, therefore linking this hormone to energy homeostasis. In incubated mouse muscle and cultured cells, gAcrp30 leads to an increase in fatty acid oxidation. This hormone is also linked to anti-atherogenesis, and in apoE (apolipoprotein)-deficien |
General description: | Acrp30 (adipocyte complement-related protein), or cytokine adiponectin, is a hormone produced and secreted by differentiated adipocytes. It is a 30kDa hydrophilic protein. This protein is composed of an N-terminal collagenous domain and a C-terminal globular trimerization domain. It exists in plasma predominantly as trimeric, hexameric or other high-molecular weight forms. The globular subunit gAcrp30 is however absent in plasma and is biologically active. gAcrp30 is the truncated form of full length of Acrp30, and functions as a ligand of AdipoR1. The Recombinant Human gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues |
Physical form: | Lyophilized from 10 mM Tris, pH 9.2 plus 0.05% Sarcosyl plus 0.75 mM DTT. |
Reconstitution: | Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
Reconstitution: | Reconstitute in water to a concentration of 1 mg/mL. This solution can then be diluted into other aqueous buffers. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |