CK2 α 2, active, GST tagged human
SIGMA/SRP5017 - PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: CK2A2; CKII-α 2; CSNK2A2
Product Type: Chemical
SDS-PAGE CK2 alpha 2, active, GST tagged, human: Cat. No. SRP5017: Purity was determined by densitometry. Molecular weight ~64 kDa. See CofA for lot-specific data.
Specific Activity CK2 alpha 2, active, GST tagged, human: Cat. No. SRP5017: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~64 kDa |
| NCBI accession no. | NM_001896   |
| product line | PRECISIO® Kinase |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 63-72 nmol/min·mg |
| storage temp. | −70°C |
| General description: | CK2α2 or casein kinase II alpha 2 is a member of the CK2 family of Ser/Thr protein kinases. CK2a2 plays a fundamental role in cell function and is involved in DNA replication, regulation of basal and inducible transcription, translation and control of metabolism. CK2α2 prefers utilization of acidic proteins such as caseins as substrates. The CK2a2 holoenzyme is a tetramer composed of an alpha chain, an alpha′ and two beta chains. The alpha and alpha′ chains contain the catalytic site. CK2α2 is also a component of CK2-SPT16-SSRP1 complex comprised of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B. This complex associates following UV irradiation. CK2a2 act as a candidate gene for inherited abnormalities of sperm morphogenesis. |
| Legal Information: | PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 63-72 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |