FGFR2 (285-end), active, GST tagged human
SIGMA/SRP5030 - PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: BFR-1; CD332; CEK3; ECT1; JWS; K-SAM; TK14; TK14; TK25
Product Type: Chemical
SDS-PAGE FGFR2 (285-end), active, GST tagged, human: Cat. No. SRP5030: Purity was determined by densitometry. Molecular weight ~72 kDa. See CofA for lot-specific data.
Specific Activity FGFR2 (285-end), active, GST tagged, human: Cat. No. SRP5030: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥80% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~72 kDa |
| NCBI accession no. | BC039243   |
| product line | PRECISIO® Kinase |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 100-136 nmol/min·mg |
| storage temp. | −70°C |
| General description: | FGFR2 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation. FGFR2 is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, and mutations in FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. FGFR2 is required for early postimplantation development between implantation and the formation of the egg cylinder. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass. |
| Legal Information: | PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥80% (SDS-PAGE) |
| activity | specific activity: 100-136 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 51111800 |