JNK2, active, GST tagged human
SIGMA/SRP5042 - PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: JNK-55; JNK2α; JNK2β; JNK2A; JNK2B; MAPK9; PRKM9; SAPK; p54a; p54aSAPK
Product Type: Chemical
SDS-PAGE JNK2, active, GST tagged, human: Cat. No. SRP5042: Purity was determined by densitometry. Molecular weight ~70 kDa. See CofA for lot-specific data.
Specific Activity JNK2, active, GST tagged, human: Cat. No. SRP5042: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~70 kDa |
| NCBI accession no. | NM_139069   |
| product line | PRECISIO® Kinase |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 11-15 nmol/min·mg |
| storage temp. | −70°C |
| Biochem/physiol Actions: | JNK2 is a member of the JNK family that acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK2 targets specific transcription factors, and mediates immediate-early gene expression in response to various cell stimuli. Both UV radiation and the proinflammatory cytokine TNFα can induce JNK2. JNK2 play a main role in the regulation of regional specific apoptosis during early brain development and providing protection against autoimmune diabetes. |
| Legal Information: | PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 11-15 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |