PTPN13 (2169-2485), active, GST tagged human
SIGMA/SRP5074 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: DKFZp686J1497; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE
Product Type: Chemical
SDS-PAGE PTPN13 (2169-2485), active, GST tagged, human: Cat. No. SRP5074: Purity was determined by densitometry. Molecular weight ~61 kDa. See CofA for lot-specific data.
Specific Activity PTPN13 (2169-2485), active, GST tagged, human: Cat. No. SRP5074: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~61 kDa |
| NCBI accession no. | NM_080683   |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| specific activity | 2040-2760 nmol/min·mg |
| storage temp. | −70°C |
| General description: | PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN13 is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. PTPN13 binds to a negative regulatory domain in Fas that inhibits Fas-induced apoptosis. |
| Physical form: | Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 2040-2760 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |