PTPN13 (2169-2485), active, GST tagged human
SIGMA/SRP5074 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: DKFZp686J1497; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE
Product Type: Chemical
assay | ≥70% (SDS-PAGE) |
form | buffered aqueous glycerol solution |
mol wt | ~61 kDa |
NCBI accession no. | NM_080683 ![]() ![]() |
recombinant | expressed in E. coli |
shipped in | dry ice |
specific activity | 2040-2760 nmol/min·mg |
storage temp. | −70°C |
General description: | PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN13 is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. PTPN13 binds to a negative regulatory domain in Fas that inhibits Fas-induced apoptosis. |
Physical form: | Supplied in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol. |
Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Purity | ≥70% (SDS-PAGE) |
activity | specific activity: 2040-2760 nmol/min·mg |
Storage Temp. | −70°C |
UNSPSC | 12352200 |