PTPRA (174-802), active, GST tagged human
SIGMA/SRP5078 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: HEPTP; HLPR; HPTPα; HPTPA; PTPA; PTPRL2; R-PTP-α; RPTPA
Product Type: Chemical
SDS-PAGE PTPRA (174-802), active, GST tagged, human: Cat. No. SRP5078: Purity was determined by densitometry. Molecular weight ~96 kDa. See CofA for lot-specific data.
Specific Activity PTPRA (174-802), active, GST tagged, human: Cat. No. SRP5078: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~96 kDa |
| NCBI accession no. | NM_002836   |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| specific activity | 1799-2435 nmol/min·mg |
| storage temp. | −70°C |
| General description: | PTPRA (also known as LRP) is a member of the protein tyrosine phosphatase family and contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. PTPRA dephosphorylates SRC family kinases, potassium channels and NMDA receptors and exists as three alternatively spliced variants which encode two distinct isoforms. Absence of PTPRA compromises correct positioning of pyramidal neurons during development of mouse hippocampus. |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 1799-2435 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |