PTPRC (592-end), active, GST tagged from mouse
SIGMA/SRP5079 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: B220; CD45R; Cd45; Ly-5; Lyt-4; T200; loc
Product Type: Chemical
SDS-PAGE PTPRC (592-end), active, GST tagged, mouse: Cat. No. SRP5079: Purity was determined by densitometry. Molecular weight ~116 kDa. See CofA for lot-specific data.
Specific Activity PTPRC (592-end), active, GST tagged, mouse: Cat. No. SRP5079: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~116 kDa |
| NCBI accession no. | NM_001111316   |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| specific activity | 8,415-11,385 nmol/min·mg |
| storage temp. | −70°C |
| Biochem/physiol Actions: | Protein tyrosine phosphatase, receptor type, C (PTPRC) has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. |
| General description: | Protein tyrosine phosphatase, receptor type, C (PTPRC) or CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 8,415-11,385 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |