RAC1, GST tagged human
SIGMA/SRP5121 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: MGC111543; MIG5; TC-25; p21-Rac1
CAS Number: 2210301-92-9
Product Type: Chemical
SDS-PAGE RAC1, GST tagged, human: Cat. No. SRP5121: Purity was determined by densitometry. Molecular weight ~47 kDa. See CofA for lot-specific data.
| application(s) | cell analysis |
| assay | ≥70% (SDS-PAGE) |
| biological source | human |
| form | buffered aqueous glycerol solution |
| mol wt | ~47 kDa |
| NCBI accession no. | NM_006908   |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| General description: | RAC1 is a member of the Rho family and is a GTPase that is part of the small GTP-binding protein superfamily. RAC1 is involved in a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Role of RAC1 in colorectal cancer has been reported after analysis of the protein expression level and activities of this protein in matched sets of tumor and non-tumor tissues. Overexpression of RAC1 leads to increased tumour growth in xenografts of human colorectal tumour cells. RAC1 is also involved in the regulation of critical cellular functions including organization of actin cytoskeleton, transcription control and cell cycle. |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |