STAT1 β, GST tagged human
SIGMA/SRP5137 - recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: DKFZp686B04100; ISGF-3; STAT91
Product Type: Chemical
SDS-PAGE STAT1 beta, GST tagged, human: Cat. No. SRP5137: Purity was determined by densitometry. Molecular weight ~118 kDa. See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~118 kDa |
| NCBI accession no. | NM_139266   |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| storage temp. | −70°C |
| General description: | STAT1β is a member of the signal transducers and activators of transcription (STAT) family of proteins that carry out a dual function: signal transduction and activation of transcription. STAT1β transcription factor is specific for the IFN pathway and plays a central role in mediating many, if not all, IFN-dependent biological responses. Presence of STAT1β leads to an efficient antiviral response when cells were infected with virus suggesting that a STAT-dependent pathway is activated following virus infection by endogenously produced IFN. Virus-induced STAT protein translocation from the cytoplasmic compartment can be detected within 3 h of infection. |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥70% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |