14-3-3 ε, GST tagged human

SIGMA/SRP5153 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym: 14-3-3 ε; 14-3-3E; FLJ45465; KCIP-1; MDCR; MDS; YWHAE

Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SRP5153-50UG	50 µg	$297.00 1/EA		Add To Favorites

SDS-PAGE 14-3-3 epsilon, GST tagged, human: Cat. No. SRP5153: Purity was determined by densitometry. Molecular weight ~55 kDa. See CofA for lot-specific data.

Properties
Descriptions
Safety Info.
Basic Data

assay	≥70% (SDS-PAGE)
form	buffered aqueous glycerol solution
mol wt	~55 kDa
NCBI accession no.	NM_006761
recombinant	expressed in E. coli
shipped in	dry ice
storage temp.	−70°C

General description:	14-3-3ε also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein is a member of the 14-3-3 family. 14-3-3ε has been reported to be involved in heat shock transcription factor 1 (HSF1) and extracellular signal regulated protein kinase (ERK) pathways. 14-3-3ε interaction with the deubiquitinating enzyme UBPY, also known as USP8, regulates cargo sorting and membrane traffic at early endosomes. Association of 14-3-3ε, HSF1 with ERK during heat shock may modulate the amplitude of the response and control the termination of HSP expression on resumption of growth conditions.
Physical form:	Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note:	after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

Purity	≥70% (SDS-PAGE)
Storage Temp.	−70°C
UNSPSC	12352202

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