14-3-3 ζ, untagged human

SIGMA/SRP5156 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym: 14-3-3 ζ; KCIP-1; MGC111427; MGC126532; MGC138156; YWHAZ

CAS Number: 1173938-18-5
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SRP5156-50UG	50 µg	$262.00 1/EA	Add To Favorites

SDS-PAGE 14-3-3 zeta, untagged, human: Cat. No. SRP5156: Purity was determined by densitometry. Molecular weight ~29kDa. See CofA for lot-specific data.

Properties
Descriptions
Safety Info.
Basic Data

application(s)	cell analysis
assay	≥70% (SDS-PAGE)
biological source	human
form	buffered aqueous glycerol solution
mol wt	~29 kDa
NCBI accession no.	NM_003406
recombinant	expressed in E. coli
shipped in	dry ice
storage temp.	−70°C

General description:	14-3-3ζ (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3ζ protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis. 14-3-3ζ protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1.
Physical form:	Supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note:	after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

Purity	≥70% (SDS-PAGE)
Storage Temp.	−70°C
UNSPSC	12352200

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