PIM3 active, GST tagged from mouse
SIGMA/SRP5228 - PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: Kid1; MGC27707; MGC37517
Product Type: Chemical
SDS-PAGE PIM3 active, GST tagged, mouse: Cat. No. SRP5228: Purity was determined by densitometry. Molecular weight ~63 kDa. See CofA for lot-specific data.
Specific Activity PIM3 active, GST tagged, mouse: Cat. No. SRP5228: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~63 kDa |
| NCBI accession no. | NM_145478   |
| product line | PRECISIO® Kinase |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 667-903 nmol/min·mg |
| storage temp. | −70°C |
| General description: | PIM3 or pim-3 oncogene belongs to a family of protooncogenes that encode serine/threonine protein kinases. Pim-3 expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines. Pim-3 also expressed in human pancreatic cancer cell and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines. |
| Legal Information: | PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 667-903 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |