TAOK3 (1-463), active, GST tagged human
SIGMA/SRP5239 - PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: DKFZp666H245; DPK; FLJ31808; JIK; MAP3K18
CAS Number: 253873-53-9
Product Type: Chemical
SDS-PAGE TAOK3 (1-463), active, GST tagged, human: Cat. No. SRP5239: Purity was determined by densitometry. Molecular weight ~89 kDa. See CofA for lot-specific data.
Specific Activity TAOK3 (1-463), active, GST tagged, human: Cat. No. SRP5239: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot-specific data.
| assay | ≥70% (SDS-PAGE) |
| biological source | human |
| form | buffered aqueous glycerol solution |
| mol wt | ~89 kDa |
| NCBI accession no. | NM_016281   |
| product line | PRECISIO® Kinase |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 221-299 nmol/min·mg |
| storage temp. | −70°C |
| technique(s) | inhibition assay: suitable |
| General description: | TAOK3 or TAO kinase 3 is a member of the serine/threonine-protein kinase family that inhibits the basal activity of Jun kinase and is negatively regulated by epidermal growth factor (EGF). Overexpression of TAOK3 may activate the ERK1/ERK2 and JNK/SAPK targets. TAOK3 is highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. |
| Legal Information: | PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Physical form: | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note: | after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 221-299 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |