KAT2A (GCN5), active, GST tagged human
SIGMA/SRP5264 - recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: GCN5; GCN5L2; HsGCN5; MGC102791; PCAF-b; hGCN5
CAS Number: 1809053-38-0
Product Type: Chemical
SDS-PAGE KAT2A (GCN5), active, GST tagged, human: Cat. No. SRP5264: Purity was determined by densitometry. Molecular weight ~82 kDa. See CofA for lot specific data.
Specific Activity KAT2A (GCN5), active, GST tagged, human: Cat. No. SRP5264: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.
| application(s) | cell analysis |
| assay | ≥70% (SDS-PAGE) |
| biological source | human |
| form | buffered aqueous glycerol solution |
| mol wt | ~82 kDa |
| NCBI accession no. | NM_021078   |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 17.6-26.4 nmol/min·mg |
| storage temp. | −70°C |
| General description: | KAT2A (K (lysine) acetyltransferase 2A) is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator which functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner. KAT2A control chromosome stability by coordinating the ATR checkpoint and double-strand break processing with autophagy. KAT2A acetyltransferases have homologous sequences and enzymatic activities which are important for recognition of nucleosomal substrates. |
| Physical form: | Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Preparation Note: | After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 17.6-26.4 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |