SRMS, active, GST tagged human
SIGMA/SRP5287 - PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: C20orf148; SRM; dJ697K14.1
Product Type: Chemical
SDS-PAGE SRMS, active, GST tagged, human: Cat. No. SRP5287: Purity was determined by densitometry. Molecular weight ~54 kDa. See CofA for lot specific data.
Specific Activity SRMS, active, GST tagged, human: Cat. No. SRP5287: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~54 kDa |
| NCBI accession no. | NM_080823   |
| product line | PRECISIO® |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 23.5-28.8 nmol/min·mg |
| storage temp. | −70°C |
| General description: | SRMS is a Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites that is involved in proliferation or differentiation of keratinocytes in the skin. SRMS functions as a rapid downstream signaling intermediate following calcium-induced differentiation in keratinocytes. SRMS constitutes a new family of non-receptor tyrosine kinases that may be redundant in function. SRMS can act either in the membrane or at the nucleus, and may change localization patterns depending on external stimuli. |
| Legal Information: | PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Physical form: | Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Preparation Note: | After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 23.5-28.8 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |