STK39 (STLK3), active, His tagged human
SIGMA/SRP5288 - PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: DCHT; DKFZp686K05124; PASK; SPAK; STK39; STLK3
Product Type: Chemical
SDS-PAGE STK39 (STLK3), active, His tagged, human: Cat. No. SRP5288: Purity was determined by densitometry. Molecular weight ~63 kDa. See CofA for lot specific data.
Specific Activity STK39 (STLK3), active, His tagged, human: Cat. No. SRP5288: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~63 kDa |
| NCBI accession no. | NM_013233   |
| product line | PRECISIO® |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 17.6-26.4 nmol/min·mg |
| storage temp. | −70°C |
| General description: | STK39 (also known as serine threonine kinase 39) is involved in the cellular stress response pathway. STK39 is activated in response to hypotonic stress leading to phosphorylation of several cation-chloride-coupled co-transporters. STK39 activates the p38 MAP kinase pathway and its interaction with p38 decreases during cellular stress. STK39 acts as an intermediate in the response to cellular stress. STK39 is also an independent risk factor for hypertension in men and its intragenic SNPs can interact and function in the control of blood pressure. |
| Legal Information: | PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC |
| Physical form: | Supplied in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol. |
| Preparation Note: | After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles. |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H360D |
| Precautionary statements | P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 17.6-26.4 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |