PIK3C2G, active, GST tagged human
SIGMA/SRP5307 - PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: MGC163149; PI3K-C2 gamma
Product Type: Chemical
assay | ≥70% (SDS-PAGE) |
form | buffered aqueous glycerol solution |
mol wt | ~110 kDa |
NCBI accession no. | BC130277 ![]() ![]() |
product line | PRECISIO® |
recombinant | expressed in baculovirus infected Sf9 cells |
shipped in | dry ice |
specific activity | 224-336 nmol/min·mg |
storage temp. | −70°C |
General description: | PIK3C2G belongs to the phosphoinositide 3-kinase (PI3K) family which plays main roles in signaling pathways and involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions and the N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. |
Legal Information: | PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC |
Physical form: | Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Preparation Note: | After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥70% (SDS-PAGE) |
activity | specific activity: 224-336 nmol/min·mg |
Storage Temp. | −70°C |
UNSPSC | 12352200 |