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DYRK2, active, GST tagged human

SIGMA/SRP5326 - PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym: FLJ21217; FLJ21365

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SRP5326-10UG 10 µg
$518.00
1/EA
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SDS-PAGE DYRK2, active, GST tagged, human: Cat. No. SRP5326: Purity was determined by densitometry. Molecular weight ~95 kDa. See CofA for lot specific data.
Specific Activity DYRK2, active, GST tagged, human: Cat. No. SRP5326: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.

 

assay ≥70% (SDS-PAGE)
form buffered aqueous glycerol solution
mol wt ~95 kDa
NCBI accession no. NM_006482 
product line PRECISIO®
recombinant expressed in E. coli
shipped in dry ice
specific activity 1000-1500 nmol/min·mg
storage temp. −70°C
General description: DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.
Legal Information: PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC
Physical form: Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note: After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥70% (SDS-PAGE)
activity specific activity: 1000-1500 nmol/min·mg
Storage Temp. −70°C
UNSPSC 12352200

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