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PIK3C2A, active, GST tagged human

SIGMA/SRP5330 - PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym: CPK; DKFZp686L193; MGC142218; PI3-K-C2(ALPHA); PI3-K-C2A

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SRP5330-10UG 10 µg
$518.00
1/EA
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SDS-PAGE PIK3C2A, active, GST tagged, human: Cat. No. SRP5330: Purity was determined by densitometry. Molecular weight ~155 kDa. See CofA for lot specific data.
Specific Activity PIK3C2A, active, GST tagged, human: Cat. No. SRP5330: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.

 

assay ≥70% (SDS-PAGE)
form buffered aqueous glycerol solution
mol wt ~155 kDa
NCBI accession no. NM_002645 
product line PRECISIO®
recombinant expressed in baculovirus infected Sf9 cells
shipped in dry ice
specific activity 16.2-25.3 nmol/min·mg
storage temp. −70°C
General description: PIK3C2A is belongs to the phosphoinositide 3-kinase (PI3K) family which play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2A can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate in vitro. PIK3C2A contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions.
Legal Information: PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC
Physical form: Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note: After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥70% (SDS-PAGE)
activity specific activity: 16.2-25.3 nmol/min·mg
Storage Temp. −70°C
UNSPSC 12352200

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