PP2C-γ, active, GST tagged human
SIGMA/SRP5334 - recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: MGC1675; MGC2870; PP2C-GAMMA; PP2CG; PPM1G; PPP2CG
Product Type: Chemical
SDS-PAGE PP2C-γ, active, GST tagged, human: Cat. No. SRP5334: Purity was determined by densitometry. Molecular weight ~105 kDa. See CofA for lot specific data.
Specific Activity PP2C-γ, active, GST tagged, human: Cat. No. SRP5334: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | ~105 kDa |
| NCBI accession no. | NM_177983   |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 1920-2880 nmol/min·mg |
| storage temp. | −70°C |
| General description: | PP2Cγ is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PP2C gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. PP2C gamma is highly expressed in testis, skeletal muscle, and heart. PP2C gamma also plays a main role in regulating cell cycle progression. |
| Physical form: | Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Preparation Note: | After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 1920-2880 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |