PP1A, active, GST tagged human
SIGMA/SRP5338 - recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym: LAR
CAS Number: 1400483-32-0
Product Type: Chemical
SDS-PAGE PP1A, active, GST tagged, human: Cat. No. SRP5338: Purity was determined by densitometry. Molecular weight ~62 kDa. See CofA for lot specific data.
Specific Activity PP1A, active, GST tagged, human: Cat. No. SRP5338: Specific Activity was determined by activity assay (see datasheet for protocol). See CofA for lot specific data.
| application(s) | cell analysis |
| assay | ≥70% (SDS-PAGE) |
| biological source | human |
| form | buffered aqueous glycerol solution |
| mol wt | ~62 kDa |
| NCBI accession no. | NM_002708   |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | 182-274 nmol/min·mg |
| storage temp. | −70°C |
| General description: | PP1A is a serine/threonine specific protein phosphatase family which is involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. PP1A is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1A functions as a suppressor of learning and memory and as a potential mediator of cognitive decline during aging.PP1A is also play a main role in splice site selection and is an important regulator of cardiac function. |
| Physical form: | Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Preparation Note: | After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥70% (SDS-PAGE) |
| activity | specific activity: 182-274 nmol/min·mg |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |