UCHL1 human
SIGMA/SRP6064 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: PARK5; PGP9.5; UCHL1; Ubiquitin carboxyl-terminal esterase L1; Uch-L1
Product Type: Product-on-demand
Immunoblotting UCHL1 Cat. No. SRP6064: SDS-PAGE of human recombinant UCHL1.
| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| form | liquid |
| mol wt | 24.8 kDa (223 aa) |
| NCBI accession no. | P09936   |
| packaging | pkg of 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| General description: | PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson′s disease susceptibility. Recombinant PGP9.5 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
| Other Notes: | MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC KAA |
| Physical form: | 1 mg/mL solution in In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM EDTA. |
| Preparation Note: | Centrifuge the vial prior to opening. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |