UCHL1 human
SIGMA/SRP6064 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: PARK5; PGP9.5; UCHL1; Ubiquitin carboxyl-terminal esterase L1; Uch-L1
Product Type: Product-on-demand
assay | ≥95% (SDS-PAGE) |
biological source | human |
form | liquid |
mol wt | 24.8 kDa (223 aa) |
NCBI accession no. | P09936 ![]() ![]() |
packaging | pkg of 100 μg |
recombinant | expressed in E. coli |
shipped in | dry ice |
storage temp. | −70°C |
General description: | PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson′s disease susceptibility. Recombinant PGP9.5 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Other Notes: | MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC KAA |
Physical form: | 1 mg/mL solution in In 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM EDTA. |
Preparation Note: | Centrifuge the vial prior to opening. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352200 |