GSTM1 from mouse
SIGMA/SRP6099 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: GST 1-1; GST class-mu1; Glutathione S-transferase Mu 1; pmGT10
Product Type: Product-on-demand
Immunoblotting GSTM1 Cat. No. SRP6099: SDS-PAGE of mouse recombinant GSTM 1.
| assay | ≥95% (SDS-PAGE) |
| biological source | mouse |
| form | liquid |
| mol wt | 25.9 kDa |
| NCBI accession no. | P10649   |
| packaging | pkg of 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | P10649 |
| Biochem/physiol Actions: | Members of GST (glutathione S-transferase) superfamily are responsible for the metabolism of various reactive oxygen species and xenobiotics. GSTM1 (GST μ 1) plays a significant role in vascular homeostasis. Humans with null allele, GSTM1(0), are at increased risks for colon and lung cancers, hypertension, and atherosclerosis, and have higher DNA changes in atherosclerotic lesions of the abdominal aorta. |
| General description: | GSTM1 (glutathione S-transferase μ 1) belongs to the superfamily of glutathione-S-transferases. It belongs to the μ class of soluble GSTs. GSTM1 is strongly expressed in the kidneys. |
| Other Notes: | MPMILGYWNV RGLTHPIRML LEYTDSSYDE KRYTMGDAPD FDRSQWLNEK FKLGLDFPNL PYLIDGSHKI TQSNAILRYL ARKHHLDGET EEERIRADIV ENQVMDTRMQ LIMLCYNPDF EKQKPEFLKT IPEKMKLYSE FLGKRPWFAG DKVTYVDFLA YDILDQYRMF EPKCLDAFPN LRDFLARFEG LKKISAYMKS SRYIATPIFS KMAHWSNK |
| Physical form: | 1 mg/mL solution in PBS (pH 7.4) containing 5 mM Glutathione |
| Preparation Note: | Centrifuge the vial prior to opening. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |