Activin B human
SIGMA/SRP6200 - recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE)
Synonym: Activin beta-B; Inhibin beta-2
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | human |
form | lyophilized powder |
mol wt | 25.6 kDa |
packaging | pkg of 10 μg |
pkg of 50 μg | |
recombinant | expressed in Hi-5 Insect cells |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | P36896 ![]() ![]() |
Biochem/physiol Actions: | Activin A and B plays a vital role in regulation of inflammation and muscle mass. Both activin A and B have a potential to act as a serum markers of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). Mutation in actin B gene is associated with the development of pre-clampsia. Serum levels of activin B can be used to differentiate tubal ectopic pregnancy (tEP) from intrauterine miscarriages (IUM) and normal viable intrauterine pregnancy (IUP). |
General description: | Human activin B, also known as inhibin β B (INHBB), is encoded by the gene mapped to human chromosome 2q14.2. It is a 25.9kDa covalently-linked homodimer consisting of two β chains, each containing 115 amino acid residues. Activin B is a transforming growth factor (TGF)-β family member. |
Physical form: | Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Citrate, pH 3.0 and 5% Trehalose. |
Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in 10 mM Sodium citrate, pH 3.0 to a concentration of 0.5 mg/mL. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |