TWEAK Receptor human
SIGMA/SRP6240 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
Synonym: FGFinducible 14; TNF-related weak inducer of apoptosis receptor; TNFRSF12A; TWEAKR
Product Type: Chemical
assay | ≥98% (SDS-PAGE) |
biological source | human |
form | lyophilized powder |
mol wt | 5.6 kDa |
packaging | pkg of 10 μg |
pkg of 50 μg | |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | Q9NP84 |
General description: | TWEAKR belongs to the TNFR superfamily of transmembrane proteins and contains a cytoplasmic “death domain,” which can activated the cell’s apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein. |
Physical form: | Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5 and 50 mM NaCl. |
Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |