BPI from human neutrophils
SIGMA/SRP6307 - ≥95% (SDS-PAGE)
Synonym: BPI; Bacterial/
Product Type: Chemical
Immunoblotting BPI/CAP57 Cat. No. SRP6307,4-12% Bis-Tris NuPAGE gel of BPI/CAP57. Lanes 1. BPI- 5 μg (Reduced/Heat) 2. BPI –10 μg (Reduced/Heat) 3. BPI– 20 μg (Reduced/Heat) 4. BRMW Standard 5. BPI– 5 μg (Non-reduced/No heat) 6. BPI – 10 μg (Non-reduced/No heat) 7. IBPI– 20 μg (Non-reduced/No heat)
| assay | ≥95% (SDS-PAGE) |
| biological source | human (neutrophils) |
| form | frozen liquid |
| mol wt | 55 kDa |
| packaging | pkg of 100 μg |
| pkg of 50 μg | |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | P17213   |
| General description: | Bactericidal/permeability increasing protein (BPI) is a 456 residue protein which is part of the innate immune system. BPI was initially identified in neutrophils, but is found in other tissues including the epithelial lining of mucus membranes. It is an endogenous antibiotic protein with potent killing activity against Gram-negative bacteria. It binds to compounds called lipopolysaccharides produced by Gram-negative bacteria. Lipolysaccharides are potent activators of the immune system; however BPI at certain concentrations can prevent this activation. Bacterial/Permeability-In |
| Physical form: | Frozen in 80 mM Citrate Phosphate, pH 5.6, 0.75 M NaCl. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |