Kininogen,HMW from human plasma
SIGMA/SRP6318 - ≥95% (SDS-PAGE)
Synonym: Alpha-2-thiol proteinase inhibitor; BDK; Fitzgerald factor; High molecular weight Kininogen; KNG; Kininogen-1 heavy chain; Kininogen-1 light chain; Low molecular weight growth-promoting; Lysyl-bradykinin; T-kinin Bradykinin; Williams-
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | human plasma |
form | frozen liquid |
mol wt | 120 kDa |
packaging | pkg of 100 μg |
shipped in | dry ice |
storage temp. | −70°C |
UniProt accession no. | P01042 ![]() ![]() |
General description: | HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease. |
Physical form: | Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352200 |