CD3G human
SIGMA/SRP6329 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: CD3-GAMMA; CD3g molecule; T3G; gamma (CD3-TCR complex)
Product Type: Chemical
assay | ≥90% (SDS-PAGE) |
biological source | human |
concentration | 1 mg/mL |
form | liquid |
impurities | <1 EU/μg endotoxin (LAL test) |
mol wt | 13.1 kDa (117 aa, 23-116 aa + His tag) |
packaging | pkg of 100 μg |
recombinant | expressed in E. coli |
shipped in | dry ice |
storage temp. | −70°C |
UniProt accession no. | P09693 |
General description: | The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor α/β and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Physical form: | 1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352200 |