CD74 human
SIGMA/SRP6333 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: DHLAG; HLA class II histocompatibility antigen gamma chain isoform b; HLADG; Ia-GAMMA
Product Type: Chemical
Immunoblotting CD74 Cat. No. SRP6333, 15% SDS PAGE (3 μg) of human recombinant CD74.
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| concentration | 0.5 mg/mL |
| form | liquid |
| impurities | <1 EU/μg endotoxin (LAL test) |
| mol wt | 20.6 kDa (183 aa, 73-232 aa + His tag) |
| packaging | pkg of 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | P04233   |
| General description: | HLA class II histocompatibility antigen gamma chain isoform b, also known as CD74, is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. CD74 is expressed by cells of both T lymphocyte and B lymphocyte lineages. It is upregulated in several cancers and is also expressed by nonimmune cells during inflammation. Recombinant human CD74 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Physical form: | 0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 1 mM DTT and 30% glycerol. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |