CD8B human
SIGMA/SRP6336 - recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
Synonym: CD8B1; LEU2; LY3; LYT3; P37; T-cell surface glycoprotein CD8 beta chain isoform 5 precursor
Product Type: Chemical
Immunoblotting CD8B Cat. No. SRP6336, 15% SDS PAGE (3 μg) of human recombinant CD8B.
| assay | ≥80% (SDS-PAGE) |
| biological source | human |
| concentration | 0.5 mg/mL |
| form | liquid |
| impurities | <1 EU/μg endotoxin (LAL test) |
| mol wt | 19.2 kDa (172 aa, 22-170 aa + His tag) |
| packaging | pkg of 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | P10966   |
| General description: | CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 β chain isoforms. Recombinant human CD8B protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Physical form: | 0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥80% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |