KLRB1 human
SIGMA/SRP6363 - recombinant, expressed in E. coli, ≥85% (SDS-PAGE)
Synonym: CD161; CLEC5B; Killer cell lectin-like receptor subfamily B member 1; NKR; NKR-P1; NKR-P1A; NKRP1A; hNKR-P1A
Product Type: Chemical
Immunoblotting KLRB1 Cat. No. SRP6363, 15% SDS PAGE (3 μg) of human recombinant KLRB1.
| assay | ≥85% (SDS-PAGE) |
| biological source | human |
| concentration | 1 mg/mL |
| form | liquid |
| mol wt | 21 kDa (183 aa, 67-225 aa + His Tag) |
| packaging | pkg of 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | Q12918   |
| General description: | Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Physical form: | 1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥85% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |