KLRK1 human
SIGMA/SRP6367 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: CD314; D12S2489E; KLR; NKG2-D; NKG2-D type II integral membrane protein; NKG2D
Product Type: Chemical
Immunoblotting KLRK1 Cat. No. SRP6367, 15% SDS PAGE (3 μg) of human recombinant KLRK1.
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| concentration | 0.5 mg/mL |
| form | liquid |
| mol wt | 19.2 kDa (168 aa, 73-216 aa + His Tag) |
| packaging | pkg of 100 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | P26718   |
| General description: | KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Physical form: | 0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |