TREM2 human
SIGMA/SRP6368 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: Trem2a; Trem2b; Trem2c; Triggering receptor expressed on myeloid cells 2
Product Type: Chemical
Immunoblotting TREM2 Cat. No. SRP6368, 15% SDS PAGE (3 μg) of human recombinant TREM2.
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| concentration | 0.25 mg/mL |
| form | liquid |
| mol wt | 20.4 kDa (181 aa, 19-161 aa + His Tag) |
| packaging | pkg of 50 μg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | Q9NZC2   |
| General description: | TREM2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The protein functions in immune response and maybe involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. Recombinant human TREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Physical form: | 0.25 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 10% glycerol. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |