CD87 human
SIGMA/SRP6379 - recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)
Synonym: CD87; MO3
Product Type: Chemical
Immunoblotting CD87 / uPAR / PLAUR Cat. No. SRP6379, SDS PAGE of human recombinant CD87/uPAR/PLAUR.
| assay | ≥92% (SDS-PAGE) |
| biological source | human |
| form | lyophilized |
| mol wt | calculated mol wt 32.1 kDa |
| observed mol wt 44-48 kDa (DTT-reduced. Protein migrates due to glycosylation. Leu 23 is the predicted N-terminus.) | |
| packaging | pkg of 20 and 100 μg |
| recombinant | expressed in HEK 293 cells |
| shipped in | wet ice |
| storage temp. | −20°C |
| tag | 6-His tagged (C-terminus) |
| UniProt accession no. | Q03405   |
| General description: | Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR act as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA. |
| Physical form: | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization. |
| Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥92% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |