CD48/BCM1/SLAMF2 human
SIGMA/SRP6387 - recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Synonym: BCM-1; BLAST; BLAST-1; BLAST1; MEM-102; SLAMF-2; TCT.1
Product Type: Chemical
Immunoblotting CD48 / BCM1 / SLAMF2 Cat. No. SRP6387, SDS PAGE of human recombinant CD48/BCM1/SLAMF2.
| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| form | lyophilized |
| impurities | <1 EU/μg endotoxin (LAL test) |
| mol wt | calculated mol wt 23.2 kDa |
| observed mol wt 38-45 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 27 is the predicted N-terminus.) | |
| packaging | pkg of 10 μg |
| pkg of 50 μg | |
| recombinant | expressed in HEK 293 cells |
| shipped in | wet ice |
| storage temp. | −20°C |
| tag | 6-His tagged (C-terminus) |
| UniProt accession no. | P09326   |
| Biochem/physiol Actions: | Eosinophil cells expressing CD48 (cluster of differentiation 48) receptors play an important role in allergic reactions induced by toxins such as those produced by Staphylococcus aureus. CD48 acts as a costimulator to activate T-lymphocytes as part of immune response. It also serves as an adhesion molecule. |
| General description: | CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation. CD48 (cluster of differentiation 48) is soluble receptor, expressed on haematopoietic cell surface. It is a glycosylphosphatidylinosi |
| Physical form: | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization. |
| Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |