CD200/OX-2 human
SIGMA/SRP6391 - recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE)
Synonym: MOX1; MOX2; MRC; My033
Product Type: Chemical
assay | ≥98% (SDS-PAGE) |
biological source | human |
form | lyophilized |
impurities | <1 EU/μg endotoxin (LAL test) |
mol wt | calculated mol wt 23.4 kDa |
observed mol wt 35-45 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 31 is the predicted N-terminus.) | |
packaging | pkg of 10 μg |
pkg of 50 μg | |
recombinant | expressed in HEK 293 cells |
shipped in | wet ice |
storage temp. | −20°C |
tag | 6-His tagged (C-terminus) |
UniProt accession no. | P41217 ![]() ![]() |
General description: | CD200 also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion. |
Physical form: | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization. |
Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |