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CNTN2/Contactin-2 human

SIGMA/SRP6447 - recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Synonym: AXT; Contactin-2; DKFZp781D102; FLJ37193; FLJ42746; MGC157722; TAG-1; TAX; TAX-1; TAX1

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SRP6447-10UG 10 µg
$0.00
1/EA
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45-SRP6447-50UG 50 µg
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Immunoblotting CNTN2/Contactin-2 Cat. No. SRP6447, SDS PAGE of human recombinant CNTN2/Contactin-2.

 

assay ≥95% (SDS-PAGE)
biological source human
form lyophilized
impurities <1 EU/μg endotoxin (LAL test)
mol wt calculated mol wt 109 kDa
  observed mol wt 140 kDa by SDS-PAGE (reducing) (Ser 31 is the predicted N-terminal .)
packaging pkg of 10 and 50 μg
recombinant expressed in HEK 293 cells
shipped in wet ice
storage temp. −20°C
UniProt accession no. Q02246 
General description: Contactin-2 also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Ig-like domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPI-specific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
Physical form: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (SDS-PAGE)
Storage Temp. −20°C
UNSPSC 12352200

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