IL7Ra/CD127 human
SIGMA/SRP6497 - recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | human |
form | lyophilized |
impurities | <1 EU/μg endotoxin (LAL test) |
mol wt | calculated mol wt 51 kDa (This protein is fused with Fc fragment of human IgG1 at the C-terminus.) |
observed mol wt 66-90 kDa (DTT-reduced. Protein migrates due to glycosylation. Glu 21 is the predicted N-terminal.) | |
packaging | pkg of 10 and 50 μg |
recombinant | expressed in HEK 293 cells |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | Q96F46 ![]() ![]() |
General description: | Interleukin-7 receptor subunit α (IL7Ra) also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R. |
Physical form: | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |