Notch-2 from mouse
SIGMA/SRP6504 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: Neurogenic Locus Notch Homolog Protein 2; Notch B
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | mouse |
form | lyophilized |
impurities | <0.01 EU/μg endotoxin (LAL test) |
mol wt | calculated mol wt ~87 kDa (The extracellular domain of mouse Notch-2 (aa 26-494) (12 epidermal growth factor-like (EGF) repeats)) |
packaging | pkg of 25 μg |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | O35516 |
General description: | Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. |
Physical form: | Lyophilized with PBS. |
Reconstitution: | Reconstitute with sterile water to 1 mg/mL. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |