Haptoglobin Plasma (MixedType) from human plasma
SIGMA/SRP6506 - ≥95% (SDS-PAGE)
Synonym: Bp; Haptoglobin b-Chain; Hp; haptoglobin a-chain
Product Type: Chemical
Immunoblotting Haptoglobin, human Plasma (Mixed Type) Cat. No. SRP6506, SDS PAGE of Haptoglobin. Lanes 1. Haptoglobin - 5 μg (reduced/heated) 2. Haptoglobin - 10 μg (reduced/heated) 3. Haptoglobin - 20 μg (reduced/heated) 4. LMW Standard 5. Haptoglobin - 5 μg (non-reduced/no heat) 6. Haptoglobin - 10 μg (non-reduced/no heat) 7. Haptoglobin - 20 μg (non-reduced/no heat)
| assay | ≥95% (SDS-PAGE) |
| biological source | human plasma |
| form | lyophilized |
| mol wt | monomer 200 kDa (Hp 2-1) |
| monomer 400 kDa (Hp 2-2) | |
| monomer 86 kDa (Hp 1-1) | |
| packaging | pkg of 1 mg |
| shipped in | wet ice |
| storage temp. | −20°C |
| UniProt accession no. | P00738   |
| General description: | An acute-phase plasma protein found in human plasma at 100-300 mg/100 mL. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype. |
| Physical form: | Lyophilized as a salt-free solid. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |