Chymotrypsin from human pancreas
SIGMA/SRP6509 - ≥95% (SDS-PAGE)
Synonym: CLCR; CTRC; CTRC_HUMAN; Caldecrin; Chymotrypsin C; Chymotrypsin-C; ELA 4; Elastase 4; Elastase IV; Serum calcium decreasing factor
EC Number: 232-671-2
Product Type: Chemical
Immunoblotting Chymotrypsin, human Pancreas Cat. No. SRP6509, SDS PAGE of Chymotrypsin, human Pancreas. Lanes 1. Chymotrypsin - 5 μg (reduced/heated) 2. Chymotrypsin - 10 μg (reduced/heated) 3. Chymotrypsin - 20 μg (reduced/heated) 4. LMW Standard 5. Chymotrypsin - 5 μg (non-reduced/no heat) 6. Chymotrypsin -10 μg (non-reduced/no heat) 7. Chymotrypsin - 20 μg (non-reduced/no heat)
| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| form | lyophilized |
| mol wt | 25 kDa |
| packaging | pkg of 100 μg |
| shipped in | wet ice |
| storage temp. | −20°C |
| UniProt accession no. | Q99895   |
| Biochem/physiol Actions: | Chymotrypsin from human pancreas selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan and leucine. Loss-of-function mutations in this gene have been associated with increased risk of chronic pancreatitis. It has high activity toward leucyl peptide bonds. The enzyme acts as a co-activator of procarboxypeptidases A1 and A2. |
| General description: | Chymotrypsin from human pancreas is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. It is secreted by the pancreas as inactive chymotrypsinogen C. Molecular weight of this enzyme is found to be 25kDa. The pI is 8.75. |
| Physical form: | Lyophilized as a salt-free solid. |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H334 - H335 |
| Precautionary statements | P261 - P280 - P284 - P304 + P340 + P312 - P337 + P313 - P342 + P311 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |