FTO from mouse
SIGMA/SRP6527 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: FATSO; Fat Mass and Obesity-associated Protein
Product Type: Chemical
assay | ≥90% (SDS-PAGE) |
biological source | mouse |
concentration | 0.5 mg/mL |
form | liquid |
impurities | <1 EU/μg endotoxin (LAL test) |
mol wt | ~55 kDa (Mouse FTO aa 2-502 is fused at the N-terminus to a His-tag.) |
packaging | pkg of 10 μg |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | Q8BGW1 |
General description: | FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. |
Physical form: | 0.5 mg/mL of 0.2 μm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |