NMNAT1 human
SIGMA/SRP6530 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: EC 2.7.7.1; NMN Adenylyltransferase 1; NaMN Adenylyltransferase 1; Nicotinamide Mononucleotide Adenylyl-transferase 1
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | human |
concentration | 1 mg/mL |
form | liquid |
mol wt | monomer ~333 kDa (Human full-length NMNAT1 aa 1-279 is fused at the N-terminus to a His-tag.) |
packaging | pkg of 10 and 50 μg |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | Q9HAN9 |
General description: | This is the nuclear NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It interacts with PARP-1/ARTD1. It protects against axonal degeneration following mechanical or toxic insults. It is widely expressed. |
Physical form: | 1 mg/mL in 50 mM sodium phosphate, pH 8.0 containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |