PEDF from mouse
SIGMA/SRP6540 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: Caspin; Pigment Epithelium-derived Factor; Serpin F1; Stromal Cell-derived Factor 3
Product Type: Chemical
| assay | ≥95% (SDS-PAGE) |
| biological source | mouse |
| form | lyophilized |
| impurities | <0.1 EU/μg endotoxin (LAL test) |
| mol wt | ~470 kDa (Mouse PEDF aa 20-417 is fused at the C-terminus to a FLAG |
| packaging | pkg of 10 μg |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage temp. | −20°C |
| UniProt accession no. | P97298   |
| General description: | Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells. |
| Physical form: | Lyophilized in PBS. |
| Reconstitution: | Reconstitute with 100 μsterile distilled water. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |