FNDC5
SIGMA/SRP6542 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym: Fibronectin Type III Domain-containing Protein 5; Fibronectin Type III Repeat-containing Protein 2
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
form | lyophilized |
impurities | <0.1 EU/μg endotoxin (LAL test) |
mol wt | ~160 kDa (extracellular domain, human aa 32-152 / mouse aa 29-149 is untagged. FNDC5 extracellular domain has 100% identity between human, mouse and rat.) |
packaging | pkg of 10 μg |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | Q8NAU1 |
General description: | Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. |
Physical form: | Lyophilized in PBS. |
Reconstitution: | Reconstitute with 100 μsterile distilled water. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |