Netrin-1 human
SIGMA/SRP6543 - recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Synonym: NTN1
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | human |
form | lyophilized |
impurities | <0.1 EU/μg endotoxin (LAL test) |
mol wt | ~800 kDa (Human netrin-1 aa 25-604 is fused at the C-terminus to a FLAG |
packaging | pkg of 10 μg |
recombinant | expressed in HEK 293 cells |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | O95631 |
General description: | Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. |
Physical form: | Lyophilized in PBS with trehalose and Brij 35. |
Reconstitution: | Reconstitute with 100 μsterile distilled water. |
Hazard statements | H412 |
Precautionary statements | P273 - P501 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |