UNC5B human
SIGMA/SRP6544 - recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Synonym: Netrin Receptor UNC5B; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; UNC5H2; p53-regulated Receptor for Death and Life Protein 1
Product Type: Chemical
assay | ≥95% (SDS-PAGE) |
biological source | human |
form | lyophilized |
impurities | <0.1 EU/μg endotoxin (LAL test) |
mol wt | ~800 kDa (The extracellular region of human UNC5B aa 28-363 is fused at the C-terminus to the Fc portion of human IgG1.) |
packaging | pkg of 10 μg |
recombinant | expressed in HEK 293 cells |
shipped in | wet ice |
storage temp. | −20°C |
UniProt accession no. | Q8IZJ1 |
General description: | UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling. |
Physical form: | Lyophilized in PBS. |
Reconstitution: | Reconstitute with 50 μsterile distilled water. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |